The increased number of tumor-associated macrophage is associated with overexpression of VEGF-C, plays an important role in Kazakh ESCC invasion and …

JM Hu, K Liu, JH Liu, XL Jiang, XL Wang… - … and molecular pathology, 2017 - Elsevier
Tumor associated macrophages (TAMs) play an important role in the growth, progression,
and metastasis of tumors. The distribution of TAMs in Kazakh esophageal squamous cell
carcinoma (ESCC) is not determined. We aimed to investigate the role of TAMs in the
occurrence and progression of Kazakh ESCC. CD163 was used as the TAM marker, and
immunohistochemistry (IHC) counts were used to quantify the density of TAMs in tumor nest
and surrounding stroma. IHC staining was used to evaluate the expression of vascular …
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